An Afghan suicide bomber has rammed a mini-bus full of expat Nato workers killing 12 people in a revenge attack over the anti-Islam film ridiculing Mohammed.
The early morning blast was the first to target Kabul since a video clip of the film was posted on the internet last week, sparking angry protests across the Muslim world.
It was also the second - and deadliest - attack in Afghanistan that militants have said they carried out as revenge strikes in response to the film.
A spokesman for the Islamist militant group Hizb-i-Islami claimed responsibility for the attack saying it was carried out by a 22-year-old woman named Fatima. Suicide bombings by women are extremely rare in Afghanistan - and few if any women drive cars.
"The anti-Islam film hurt our religious sentiments and we cannot tolerate it," the spokesman said.
"There had been several young men who wanted to take revenge but Fatima also volunteered and we wanted to give a chance to a girl for the attack to tell the world we cannot ignore any anti-Islam attack."
He warned of more attacks against foreigners working for Nato.
The bombing was an escalation of violence in the capital, where most attacks are usually blamed on the Haqqani network - a Pakistan-based militant group affiliated with the Taliban and al Qaida.
Eight of the dead were South Africans believed to be working for an aviation company based at Rand Airport in Johannesburg. Four Afghans also were killed and another 11 Afghan civilians were wounded.
The blast came a day after hundreds of Afghans burned cars and threw stones at a US military base in the capital in a demonstration against the anti-Islam film.