Madeleine McCann's parents have spoken of their renewed hope that their daughter will be found alive five years after she went missing.
Kate and Gerry McCann said they have received a major boost from Scotland Yard's review of the case, and have "no doubt" that the Portuguese authorities will eventually re-open their investigation.
In a series of interviews on the eve of the fifth anniversary of Madeleine's disappearance, the couple also said their seven-year-old twins Sean and Amelie have pledged to join the search for their big sister when they are older.
Mr McCann, 43, said: "I'm certainly more confident now than at any point for the last four-and-a-half years that we actually will find Madeleine and who is responsible."
He added: "I think the most important thing is that a lot of the investigation opportunities are in Portugal.
"I think it's fairly clear that the case will have to be re-opened for those to be pursued adequately.
"We weren't expecting a knee-jerk reaction by any means. This is an ongoing dialogue, and I am sure the investigation will get opened again in due course. I have no doubt about that."
The officer leading Scotland Yard's review of the original investigation into Madeleine's disappearance spoke last week of his belief that the mystery can still be solved and said there is evidence she may still be alive.
Detective Chief Inspector Andy Redwood said the Metropolitan Police would like the case to be re-opened, but stressed that the decision was one for Portugal.
But Portuguese police responded by saying they had found "no new element" to justify re-launching their inquiry.